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Figure 2 | Biology Direct

Figure 2

From: Parameters of proteome evolution from histograms of amino-acid sequence identities of paralogous proteins

Figure 2

Illustration of dynamical processes changing the PID histogram. (panel A) The PID decay generates a negative flux v(p)N a (p) down the PID-axis. The net flux into a given bin Δp is given by v(p + Δp)N a (p + Δp) - v(p)N a (p) ≈ Δ p d d p [ v ( p ) N a ( p ) ] MathType@MTEF@5@5@+=feaafiart1ev1aaatCvAUfKttLearuWrP9MDH5MBPbIqV92AaeXatLxBI9gBaebbnrfifHhDYfgasaacPC6xNi=xH8viVGI8Gi=hEeeu0xXdbba9frFj0xb9qqpG0dXdb9aspeI8k8fiI+fsY=rqGqVepae9pg0db9vqaiVgFr0xfr=xfr=xc9adbaqaaeGacaGaaiaabeqaaeqabiWaaaGcbaGaeuiLdqKaemiCaaxcfa4aaSaaaeaacqWGKbazaeaacqWGKbazcqWGWbaCaaGccqGGBbWwcqWG2bGDcqGGOaakcqWGWbaCcqGGPaqkcqWGobGtdaWgaaWcbaGaemyyaegabeaakiabcIcaOiabdchaWjabcMcaPiabc2faDbaa@4026@ (panel B) A single gene duplication event AA' gives rise to three new paralogous pairs: A' - A, A' - B and A' - C. Immediately after the duplication the pair A - A' has the PID = 100%, while PIDs of A' - B and A' - C are equal to those of A - B and A - C. Thus the PID of every previously existing paralogous pair involving A gets duplicated along with the duplication AA'.

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