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Figure 1 | Biology Direct

Figure 1

From: Small but versatile: the extraordinary functional and structural diversity of the β-grasp fold

Figure 1

Topology diagrams of selected β-GF members. A generalized representative is shown in (A) with the key structural features found in certain lineages of the fold labeled, while (B) depicts idealized versions of specific lineages, the names of which are given above the diagrams. Strands are shown as arrows with the arrowhead at the C-terminal end. Strands belonging to the 4-stranded β-GF core are colored green, the additional strand found in the 5-stranded assemblage is colored yellow, strands forming a conserved insert within the β-GF scaffold are colored magenta, and other strands specific to a certain lineage are colored grey and outlined with a broken line. Helices are depicted as rectangles, with the core absolutely conserved helix colored orange and other helices specific to a certain lineage colored grey and outlined with a broken line. The diagrams are grouped and labeled in a manner consistent with the structural classes described in the text, with members of the eukaryotic UB-like superfamily nested within other members of the 5-stranded assemblage. The 2Fe-2S cluster of the ferredoxins is shown as four small ovals bound to cysteine residues represented by the letter "C".

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