Table 1 Proteins localized in the peroxisome in S. cerevisiae and R. norvegicus. Gene names are from SGD, Swissprot or GeneBank. Proteins in the same row are orthologous to each other, whenever there is a "one to many" orthology relationship this is indicated by boxes containing several rows. Absence of the gene or absence of evidence of a peroxisomal localization of the encoded protein is indicated by a dash. Proteins that show homology with components of the ERAD pathways are indicated with names in bold and a comment indicating that homology. For each orthologous group, the annotated function and the phylogenetic origin is indicated (euk: eukaryotic no bacterial homologs; euk (a.o.): presence of bacterial homologs but the phylogenetic reconsructions indicates an ancient origin derived from the common ancestor of eukaryotes and archaea; alpha: alpha-proteobacterial origin; actinomyc.: derived from the actinomycetales; cyanobac.: cyanobacterial origin; u, unresolved phylogenetic origin.

Peroxisome organization and biogenesis (Homologous to ERAD protein Cdc48)

Peroxisome organization and biogenesis (Homologous to ERAD protein Hrd1)

Peroxisome organization and biogenesis

Peroxisome organization and biogenesis (Homologous to ERAD protein Ubc1)

Peroxisome organization and biogenesis (Homologous to ERAD protein Hrd3)

Peroxisome organization and biogenesis

Peroxisome organization and biogenesis

Peroxisome organization and biogenesis

Peroxisome organization and biogenesis (Homologous to ERAD protein Hrd1)

Peroxisome organization and biogenesis

Peroxisome organization and biogenesis

Peroxisome organization and biogenesis

Peroxisome organization and biogenesis

Peroxisome organization and biogenesis

Peroxisome organization and biogenesis

Peroxisome organization and biogenesis

Peroxisome organization and biogenesis

Peroxisome organization and biogenesis

Peroxisome organization and biogenesis

Peroxisome organization and biogenesis

Peroxisome organization and biogenesis

Peroxisome organization and biogenesis

Peroxisome organization and biogenesis

Peroxisome organization and biogenesis

Peroxisome organization and biogenesis

Peroxisome organization and biogenesis

Peroxisome organization and biogenesis

Peroxisome organization and biogenesis

Adenine nucleotide transporter

Peroxisomal membrane protein

Peroxisomal membrane protein

Phytanoyl-CoA dioxygenase

2-hydroxyphytanoyl-CoA lyase

peroxisomal long chain acyl-CoA thioesterase Ib

Peroxisomal acyl-coenzyme A thioester hydrolase 1

Catalase A

acyl-CoA oxidase

peroxisomal multifunctional beta-oxidation protein

peroxisomal 3-oxoacyl CoA thiolase

Peroxisomal bifunctional enzyme

sterol carrier protein-2

Peroxisomal NADP-dependent isocitrate dehydrogenase

enoyl-CoA isomerase

bile acid-Coenzyme A: amino acid N-acyltransferase

alkyl-dihydroxyacetonephosphate synthase

Dihydroxyacetone phosphate acyltransferase

alanine-glyoxylate aminotransferase

pipecolic acid oxidase

Urate oxidase

fatty acid transport

Long-chain-fatty-acid--CoA ligase

Fatty acid transport

Hydroxyacid oxidase 3 (medium-chain)

Hydroxyacid oxidase 1

Glutathyhion-S transferase

2-arylpropionyl-CoA epimerase

Peroxisome fission

probable AMP-binding protein

Citrate synthase

glycerol-3-phosphate dehydrogenase

malate dehydrogenase

Lysine biosynthesis, saccharopine dehydrogenase

Lysine biosynthesis

NAD(+) salvage pathway

NADH diphosphatase (pyrophosphatase)

Sulfur Transfer

Malate synthase 1

Malate synthase 2

Vesicle organization and biogenesis

Ergosterol biosynthesis

Ergosterol biosynthesis

GTP-binding protein

2,4-dienoyl-CoA reductase

Peroxisome organization and biogenesis

Carnitine acetyltransferase

Nudix hydrolase

Aspartate aminotransferase

Peroxisomal ATP-binding cassette, fatty acid transport

Dynamin 1