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Table 1 Proteins localized in the peroxisome in S. cerevisiae and R. norvegicus. Gene names are from SGD, Swissprot or GeneBank. Proteins in the same row are orthologous to each other, whenever there is a "one to many" orthology relationship this is indicated by boxes containing several rows. Absence of the gene or absence of evidence of a peroxisomal localization of the encoded protein is indicated by a dash. Proteins that show homology with components of the ERAD pathways are indicated with names in bold and a comment indicating that homology. For each orthologous group, the annotated function and the phylogenetic origin is indicated (euk: eukaryotic no bacterial homologs; euk (a.o.): presence of bacterial homologs but the phylogenetic reconsructions indicates an ancient origin derived from the common ancestor of eukaryotes and archaea; alpha: alpha-proteobacterial origin; actinomyc.: derived from the actinomycetales; cyanobac.: cyanobacterial origin; u, unresolved phylogenetic origin.

From: Origin and evolution of the peroxisomal proteome

S. cerevisiae R. norvegicus Origin Function (comment)
PEX1 PEX1 euk (a.o) Peroxisome organization and biogenesis (Homologous to ERAD protein Cdc48)
PEX2 PEX2 euk Peroxisome organization and biogenesis (Homologous to ERAD protein Hrd1)
PEX3 PEX3 euk Peroxisome organization and biogenesis
PEX4 PEX4 Euk Peroxisome organization and biogenesis (Homologous to ERAD protein Ubc1)
PEX5 PEX5 euk (a.o) Peroxisome organization and biogenesis (Homologous to ERAD protein Hrd3)
PEX6 PEX6 euk (a.o) Peroxisome organization and biogenesis
PEX7 PEX7 Euk Peroxisome organization and biogenesis
PEX8 - Euk Peroxisome organization and biogenesis
PEX10 PEX10 Euk Peroxisome organization and biogenesis (Homologous to ERAD protein Hrd1)
- PEX11 euk (a.o) Peroxisome organization and biogenesis
PEX12 PEX12 euk Peroxisome organization and biogenesis
PEX13 PEX13 euk Peroxisome organization and biogenesis
PEX14 PEX14 euk (a.o) Peroxisome organization and biogenesis
PEX15 - euk Peroxisome organization and biogenesis
- PEX16 euk Peroxisome organization and biogenesis
PEX17 - euk Peroxisome organization and biogenesis
PEX18 - euk Peroxisome organization and biogenesis
PEX19 PEX19 euk Peroxisome organization and biogenesis
PEX21 - euk Peroxisome organization and biogenesis
PEX22 - euk Peroxisome organization and biogenesis
PEX25 - euk Peroxisome organization and biogenesis
- PEX26 euk Peroxisome organization and biogenesis
PEX27 - euk Peroxisome organization and biogenesis
PEX28 - euk Peroxisome organization and biogenesis
PEX29 - euk Peroxisome organization and biogenesis
PEX30 - euk Peroxisome organization and biogenesis
PEX31 - euk Peroxisome organization and biogenesis
PEX32 - euk Peroxisome organization and biogenesis
ANT1 PMP34 euk Adenine nucleotide transporter
- PMP24 euk Peroxisomal membrane protein
- PMP22 euk Peroxisomal membrane protein
- PAHX U Phytanoyl-CoA dioxygenase
- gi-6912418 U 2-hydroxyphytanoyl-CoA lyase
- PTE2B alpha peroxisomal long chain acyl-CoA thioesterase Ib
TES1 PTE1_MOUSE alpha Peroxisomal acyl-coenzyme A thioester hydrolase 1
CTA1 CATALASE euk (a.o) Catalase A
FOX1 OXRTA2 U acyl-CoA oxidase
gi-1684747 U   
CAO3_RAT U   
FOX2 gi-13242303 alpha peroxisomal multifunctional beta-oxidation protein
gi-4105269 alpha putative peroxisomal 2,4-dienoyl-CoA reductase  
gi-5052204 alpha putative short-chain dehydrogenase/reductase  
FOX3 gi-6978429 U peroxisomal 3-oxoacyl CoA thiolase
- ECHP_RAT U Peroxisomal bifunctional enzyme
- SCP2 U sterol carrier protein-2
IDP3 gi-13928690 U Peroxisomal NADP-dependent isocitrate dehydrogenase
ECI1 gi-6755026 alpha enoyl-CoA isomerase
DCI1 alpha   
- BAAT alpha bile acid-Coenzyme A: amino acid N-acyltransferase
- gi-12002203 actinomyc. alkyl-dihydroxyacetonephosphate synthase
- DAPT_RAT actinomyc. Dihydroxyacetone phosphate acyltransferase
- AGT cyanobac. alanine-glyoxylate aminotransferase
- gi-6679507 U pipecolic acid oxidase
- URIC_RAT U Urate oxidase
PXA1 PMP70 U fatty acid transport
ALDP U ATP-binding cassette  
ALDPR U ATP-binding cassette  
FAA1 - euk  
FAA2 LCF2 U Long-chain-fatty-acid--CoA ligase
LACS U   
FAT1 VLACS U Fatty acid transport
- gi-14091775 U Hydroxyacid oxidase 3 (medium-chain)
- gi-6754156 U Hydroxyacid oxidase 1
- GTK1_RAT U Glutathyhion-S transferase
- AMCR U 2-arylpropionyl-CoA epimerase
- FIS1 euk Peroxisome fission
FAT2 - alpha probable AMP-binding protein
CIT2 - U Citrate synthase
GPD1 - alpha glycerol-3-phosphate dehydrogenase
MDH3 - U malate dehydrogenase
LYS1 - euk Lysine biosynthesis, saccharopine dehydrogenase
LYS4 - U Lysine biosynthesis
PNC1 - U NAD(+) salvage pathway
NPY1 - alpha NADH diphosphatase (pyrophosphatase)
STR3 - U Sulfur Transfer
YGR154C - U  
MLS1 - U Malate synthase 1
MLS2 - U Malate synthase 2
EMP24 - euk Vesicle organization and biogenesis
ERG1 - U Ergosterol biosynthesis
ERG6 - U Ergosterol biosynthesis
RHO1 - euk GTP-binding protein
SPS19 - U 2,4-dienoyl-CoA reductase
YOR084W - euk Peroxisome organization and biogenesis
YMR204C - euk  
CAT2 - euk Carnitine acetyltransferase
PCD1 - alpha Nudix hydrolase
AAT2 - euk Aspartate aminotransferase
PXA2 - U Peroxisomal ATP-binding cassette, fatty acid transport
VPS1 - euk Dynamin 1