Figure 7

Solutions of system (13)–(14) with both uninfected cell specific and infected cell specific distributions of transmission coefficient β. β₁ is gamma-distributed on [0.6, ∞) and β₂ is beta-distributed on [0,2.5]. Uninfected cells, X(t), infected cells, Y(t), and the total tumor load, X(t) + Y(t), are shown in blue, green and black, respectively. The initial means of distributions are $E_{{\beta }_1}$ (0) = 2.9 and $E_{{\beta }_2}$ (0) = 0.6, initial variances are ${\sigma }_{{\beta }_1}^2$ (0) = 1.9 and ${\sigma }_{{\beta }_2}^2$ (0) = 0.12 (a) ${\sigma }_{{\beta }_2}^2$ (0) = 0.11 (b). In panels (c) and (d), the mean parameter values $E_{{\beta }_1}$ (t), $E_{{\beta }_2}$ (t) and E(t) = $E_{{\beta }_1}$ (t) $E_{{\beta }_2}$ (t) are shown for cases (a) and (b), respectively