Generalization of DNA microarray dispersion properties: microarray equivalent of t-distribution

Biology Direct

Table 2 Percentage of samples failing the Kolmogorov-Smirnov normality test

Array	Materials	No. of arrays	No. of probe sets	Threshold	% failure (total)	% failure (above)	% failure (below)
Affy. HuGeneFL	human cell line SKBR [a]	5	7070	2.7	7.2	6.9	7.8
Affy. HuGeneFL	human cell line IMR90 [a]	11	7070	4.1	6.3	6.5	5.9
Affy. U74Av2	murine lung tissue [b]	5	12422	10.0	6.1	6.6	5.5
Affy. U74Av2	murine lung tissue [c]	5	12422	13.6	7.6	8.3	6.4
Affy. U74Av2	murine lung tissue [d]	11	12422	14.2	10.6	10.6	10.7
Affy. Focus	human blood cell line [e]	9	8746	5.0	6.14	6.14	6.14
Illumina 1	human cell line GM10469 [f]	4	633	2.1	4.6	3.9	6.2
Illumina 2	human cell line GM10469 [f]	4	633	3.6	6.5	6.6	6.2
Average	---	---	---	---	6.9	6.9	6.9

Percentage of samples failing the Kolmogorov-Smirnov normality test at the level P = 0.05. All arrays are normalized to 100% of the mean value. The columns %failure (above) and %failure (below) give percentage of failures above and below the specified threshold.
[a] data Ref. [10].
[b] C57BL/6 (B6) WT mice, data Ref. [15].
[c] C57BL/6-Cftr-/- KO inbred mice, data Ref. [15].
[d] data M. Cosio.
[e] data O. Modlich and S. Raschke.
[f] lymphoblast cell line GM10469 [8].

ISSN: 1745-6150