Generalization of DNA microarray dispersion properties: microarray equivalent of t-distribution

Biology Direct

Table 1 Illustration of the consecutive sampling procedure

Rank	Probe set	Sample Y1	Sample Y2	Y2-Y1	(Y2+Y1)/2	Sample Mean	SD (Y2-Y1)	SD(Y1)+ SD(Y2)
	...	...	...	...	...
251	J03040_at	628	614	-14	621	614.4	71.1	71.8
252	M26880_at	657	583	-74	620
253	HG384-HT384_at	577	662	86	619
254	X04654_s_at	633	604	-29	619
255	J04046_s_at	554	680	126	617
256	X69908_rna1_at	593	640	47	617
257	D85758_at	672	555	-117	614
258	L12168_at	633	592	-41	612
259	HG1614-HT1614_at	590	633	43	611
260	X71428_at	571	649	77	610
261	S75463_at	602	615	13	608
262	X69910_at	579	630	50	604
263	X57346_at	597	610	13	603	590.1	136.2	137.0
264	U01691_s_at	576	630	54	603
265	X17620_at	605	594	-11	600
266	U10323_at	562	617	56	590
267	AJ001421_at	413	766	354	589
268	X62654_rna1_at	576	602	26	589
269	D64142_at	666	510	-156	588
270	D21063_at	562	613	51	588
271	X16560_at	588	580	-8	584
272	D26600_at	580	586	6	583
273	M19267_s_at	599	566	-33	583
274	J02621_s_at	688	475	-213	582
...	...	...	...	...	...

Rank shows the rank from the highest mean expression. The columns "Sample Y1 and Y2" give the expression values, Y₂ - Y₁ is the expressions difference and (Y2+Y1)/2 the mean expression of the probe sets Y1 and Y2. Sample Mean is the mean expression of the sample, "D(Y2-Y1)" is the standard deviation obtained from the difference of expressions and SD(Y1)+SD(Y2) is the sum of the standard deviations calculated from the values Y1 and Y2, respectively. The first 250 probe pairs are excluded to keep variation of the mean expression within the sample small.

ISSN: 1745-6150