Domain neighborhoods for the S-helix. The architectural context in which the S-helix occurs along with its immediately adjacent domains is shown here. The lower bound of numbers of such contexts in different proteins from 255 completely sequenced domains is shown to the right. The two contexts with the numbers in the green boxes are seen in animals. The domain abbreviations are as in section 2 Materials and Methods and Figure 4. The grey boxes are uncharacterized domains.