Clinical applications of Genome Polymorphism Scans

Biology Direct

Table 2 Minimum STRP^a densities required for Scan applications

APPLICATION	MINIMUM NUMBERS OF STRPS
Gender determination	10
Family tree construction	10
Individual identification	10
Chimerism discovery	100
Aneusomy detection	500
Uniparental disomy detection	500
Autozygosity determination	500
Inbreeding measurement	500
Linkage mapping	500
Geoancestry estimation	500
Haplotype determination	500
Propagation of genetic information	1000
Genotyping error detection	1000
Association mapping	2000

^a A rough estimate of the equivalent numbers of diallelic polymorphisms can be obtained by multiplying the numbers of STRPs by 4.

ISSN: 1745-6150