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Figure 2 | Biology Direct

Figure 2

From: Distinguishing HIV-1 drug resistance, accessory, and viral fitness mutations using conditional selection pressure analysis of treated versus untreated patient samples

Figure 2

Positive selection pressure in the Specialty andTreated datasets. K a /K s values for positive selection pressures in the Specialty and Treated datasets are plotted. K a /K s values with a LOD < 2 in the Treated dataset were plotted as empty triangles. Different colors represent codons with different functions on drug resistance: Red: primary drug resistance mutation codon; Blue: accessory drug resistance mutation codon; Light blue: function unknown codon. The correlation coefficient of the selection pressures in these two datasets is 0.887, suggesting a significant quantitative agreement.

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