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Figure 1 | Biology Direct

Figure 1

From: Distinguishing HIV-1 drug resistance, accessory, and viral fitness mutations using conditional selection pressure analysis of treated versus untreated patient samples

Figure 1

Conditional Ka/Ks measurements for primary vs. accessory drug-resistance mutations. For the two possible pathways from wildtype to a double mutant, we computed the conditional K a /K s values for each mutation conditioned on the presence or absence of the other mutation (shown as numbers next to each edge in the figure). Primary drug resistance codons are highlighted in bold. a) 24/82; b) 54/89; c, e, g) 10/90; d, f, h) 63/90. a-d are from the Specialty dataset; e-f from the Treated dataset; and g-h from the Untreated dataset (see text).

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Biology Direct

ISSN: 1745-6150

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