Fig. 7

Osteogenic Efficacy of MOF-Fe In Vivo. A: Sirius Red staining of femur sections at various time points for the control and MOF-Fe-treated groups at different concentrations. B: Femur sections from the control and MOF-Fe-treated groups observed with Perl’s staining, with iron ion deposition indicated by black arrows. C: Immunohistochemical staining for BMP2 in femur sections from the control group and the groups treated with various concentrations of MOF-Fe. D: Quantitative analysis of BMP2 immunohistochemical staining intensity. E: Hydrogel scaffolds containing MOF-Fe at various concentrations. F: The efficacy of bone defect repair in rabbit cranial bones 30 days post-implantation with hydrogel scaffolds containing different concentrations of MOF-Fe. The data are presented as the means ± SDs for n = 3. *p < 0.05, **p < 0.01