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Fig. 8 | Biology Direct

Fig. 8

From: ZNF692 promotes osteosarcoma cell proliferation, migration, and invasion through TNK2-mediated activation of the MEK/ERK pathway

Fig. 8

ZNF692-TNK2 axis is an attractive candidate as a prognostic biomarker of osteosarcoma. (A) The proportion of patients in different sub-groups stratified by the number of up-regulated marker genes. ZNF692 and TNK2 expression was stratified by the corresponding medians by RNA-sequencing data from TCGA dataset, and the patients were divided into three groups as indicated. (B) Kaplan-Meier analysis of overall survival for osteosarcoma patients based on the number of upregulated marker genes. (C) Univariate and multivariate Cox regression analysis of the number of up-regulated makers and clinical features including gender and age in patients with osteosarcoma in TCGA database

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