Fig. 7

USP40 promotes tumor growth in vivo. A Stable transfection of MHCC97H cells with shNC or shUSP40 were subcutaneously inoculated into nude mice, and the mice were euthanized 30 days later and the tumors were dissected to obtain images of tumors. B, C showed the tumor size and weight of nude mice. D USP40 and Claudin1 expression in tumor samples was tested by western blotting. E The picture displayed subcutaneous tumors formed by MHCC97H cells in overexpressed USP40 or NC group. F, G showed the tumor size and weight of nude mice. H USP40 and Claudin1 expression in tumor samples was examined by western blotting. Data were displayed with typical pictures of three independent experiments. *P < 0.05, **P < 0.01, ***P < 0.001