Fig. 2
From: RPL35A promotes the progression of cholangiocarcinoma by mediating HSPA8 ubiquitination
Knockdown of RPL35A inhibited CCA cell proliferation and migration (A) The proliferation of HCCC-9180 and HUCCT1 cells after RPL35A knockdown was detected by Celigo cell count assay. (B) The results of flow cytometry showed increased apoptosis in HCCC-9180 and HUCCT1 cells after RPL35A knockdown. (C) Flow cytometry was used to assess the role of RPL35A in the cycle progression of HCCC-9180 and HUCCT1 cells. (D) Transwell assay was performed to evaluate the effect of RPL35A knockdown on the migration of HCCC-9180 and HUCCT1 cells. (E) Wound healing assay was applied to verify the effect of RPL35A knockdown on the migration of HCCC-9180 and HUCCT1 cells. *P < 0.05, **P < 0.01, ***P < 0.001