Fig. 1
From: RPL35A promotes the progression of cholangiocarcinoma by mediating HSPA8 ubiquitination
RPL35A was upregulated in CCA (A) The heat map displayed the significantly differentially expressed genes in CCA. The data were obtained from TCGA database and analyzed by R software. (B) The RPL351 levels in CCA and normal samples was predicted by GEPIA online tool. (C) Immunohistochemical staining was used to evaluate the expression of RPL35A protein in normal bile duct tissues and CCA tissues. (D) Kaplan-Meier survival analysis shows that high expression of RPL35A has poorer survival. (E) RPL35A expression in 4 CCA cell lines (HCCC-9180, HUCCT1, QBC-939, and RBE) and human intrahepatic biliary epithelial cell line (HIBEC cells) was detected by RT-qPCR. *P < 0.05, **P < 0.01, ***P < 0.001