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Fig. 5 | Biology Direct

Fig. 5

From: PLAU promotes growth and attenuates cisplatin chemosensitivity in ARID1A-depleted non-small cell lung cancer through interaction with TM4SF1

Fig. 5

Overexpression of TM4SF1 promotes NSCLC cell proliferation and survival. (A) Western blot analysis of TM4SF1 protein levels in vector- and TM4SF1-overexpressing cells. GAPDH was used as a loading control. (B) Assessment of cell proliferation by direct counting. *P < 0.05. (C) Cell proliferation as measured by EdU assay. *P < 0.05. (D) Colony formation assay. *P < 0.05. (E) NSCLC cells transfected with indicated plasmids were tested for apoptosis after culturing in the presence or absence of serum for 48 h. *P < 0.05. (F) NSCLC cells transfeced with indicated plasmids were treated with different concentrations of cisplatin for 72 h before viability assessment by the MTT method

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