Variables | Univariate analysis HR (CI 95%) | P value | Multivariate analysis HR (CI 95%) | P value |
---|---|---|---|---|
AGE | 1.032 (0.999–1.066) | 0.057 | ||
SEX | 0.840 (0.324–2.178) | 0.720 | ||
WBC | 1.001 (0.995–1.006) | 0.821 | ||
Hb | 1.000 (0.982–1.018) | 0.991 | ||
PLT | 1.001 (0.998–1.003) | 0.671 | ||
BRAF expression | 1.042 (1.015–1.069) | 0.002 | 1.027 (0.991–1.064) | 0.140 |
AGE ≥ 48 years | 0.599 (0.227–1.582) | 0.301 | ||
WT1 mutated and wt | 0.770 (0.272–2.174) | 0.621 | ||
FLT3-ITD mutated and wt | 2.078 (0.582–7.418) | 0.260 | 1.176 (0.310–4.455) | 0.812 |
NPM1 mutated and wt | 0.589 (0.077–4.479) | 0.609 | ||
DNMT3A mutated and wt | 1.332 (0.302–5.882) | 0.705 | ||
TET2 mutated and wt | 0.045 (0.000–526.014) | 0.517 | ||
C-KIT mutated and wt | 0.556 (0.072–4.278) | 0.573 | ||
FLT3-TKD mutated and wt | 1.344 (0.176–10.238) | 0.775 | ||
IDH1 mutated and wt | 0.047 (0.000–9361.29) | 0.624 | ||
SRSF mutated and wt | 0.048 (0.00–55212.04) | 0.669 | ||
ASXL1 mutated and wt | 0.048 (0.00–162969.9) | 0.692 | ||
NRAS mutated and wt | 0.047 (0.000–5527.25) | 0.607 | ||
IDH2 mutated and wt | 0.047 (0.00–13658.72) | 0.634 | ||
Risk category | 0.488 (0.246–0.969) | 0.041 | 0.818 (0.326–2.054) | 0.669 |
Treatment regimen | 0.294 (0.125–0.692) | 0.005 | 0.404 (0.177–0.923) | 0.032 |