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Fig. 2 | Biology Direct

Fig. 2

From: Vemurafenib induces senescence in acute myeloid leukemia and myelodysplastic syndrome by activating the HIPPO signaling pathway: implications for potential targeted therapy

Fig. 2

High BRAF expression was correlated with age and gene mutation in AML. A The distribution of age in AML patients with low and high BRAF expression; B A merged score for BRAF expression prediction established by nomogram based on the age, gene mutations and other clinical characters; C Heat map of AML patients grouped by age and BRAF expression level; D Survival analysis of AML patients based on age and BRAF transcript level; E Survival analysis of AML patients based on DNMT3A mutation and BRAF transcript level; F Survival analysis of AML patients based on TET2 mutation and BRAF transcript level; G Survival analysis of AML patients based on WT1 expression and BRAF transcript level; H Survival analysis of AML patients based on FLT3-ITD mutation and BRAF transcript level; I Survival analysis of AML patients based on NPM1 mutation and BRAF transcript level

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