Fig. 6
From: DTX2 promotes glioma development via regulation of HLTF
DTX2/HLTF axis contributes to glioma cell proliferation and migration through HLTF. A The expression of DTX2 and HLTF was detected DTX2 knock down and double knock down of DTX2 and HLTF (shDTX2#1 + shHLTF#1) in U87 and U251 cells by western blot. B, C The role of DTX2 and HLTF knock down in glioma cell proliferation was detected in U87 and U251 cells using the CCK-8 assay. (***P < 0.001). D Numbers of colonies formed by U87 and U251 cells with DTX2 knock down and double knock down of DTX2 and HLTF (shDTX2#1 + shHLTF#1) in U87 and U251 cells (***P < 0.001). E The effects of DTX2 and HLTF knock down in glioma cell migration were investigated using a Transwell assay. (***P < 0.001)