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Fig. 1 | Biology Direct

Fig. 1

From: Dysregulation and antimetastatic function of circLRIG1 modulated by miR-214-3p/LRIG1 axis in bladder carcinoma

Fig. 1

Expression of circLRIG1 in bladder carcinoma. A Analysis of circLRIG1 expression in bladder carcinoma tissues and adjacent noncancerous specimens using the GSE92675 database. B qRT-PCR analysis of circLRIG1 mRNA levels in 90 pairs of bladder carcinoma tissues and adjacent noncancerous specimens. C K-M survival analysis of bladder carcinoma patients with low or high expression of circLRIG1. D qRT-PCR analysis of circLRIG1 mRNA levels in normal urothelial cell line SV-HU-1 and 11 bladder carcinoma cell lines (UM-UC-14, SW780, TUCCUP, 5637, J82, UMUC3, BIU87, T24, HT1367, EJ and RT4). E qRT-PCR analysis of circLRIG1 and LRIG1 mRNA levels in bladder carcinoma cell lines (UMUC3 and T24) treated with Actinomycin D. F qRT-PCR analysis of circLRIG1 and LRIG1 mRNA levels in bladder carcinoma cell lines (UMUC3 and T24) with or without RNase R treatment. G Subcellular localization of circLRIG1 in bladder carcinoma cell lines (UMUC3 and T24) confirmed by cytosolic/nuclear fractionation assay. Experiments were performed in triplicate. “**” indicates P < 0.01

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