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Fig. 4 | Biology Direct

Fig. 4

From: Spinal apolipoprotein E is involved in inflammatory pain via regulating lipid metabolism and glial activation in the spinal dorsal horn

Fig. 4

Differentially expressed genes (DEGs) between Apoe−/− and C57BL6 (C57) mice after complete Freund’s adjuvant (CFA) treatment. A Volcano plot of 63 DEGs between CFA-treated C57 and Apoe−/− mice. B Heatmap of 26 DEGs determined based on log2 (fold change (FC)) > 0.5 or <  − 0.5. C The enrichment of DEGs in the Gene Ontology (GO) term molecular function. D The enrichment of DEGs in the GO term biological process. E Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis of 63 DEGs. F Protein–protein interaction (PPI) network of 63 DEGs, including Apoe, Jun, Cx3cr1, and C1qa

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