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Fig. 7 | Biology Direct

Fig. 7

From: Loss of the centrosomal protein ALMS1 alters lipid metabolism and the regulation of extracellular matrix-related processes

Fig. 7

Study of cross-signalling between TGF-β and AKT pathways in ALMS1KO cell models. (A) Representative Western blot of AKT overactivation after TGF-β pathway stimulation in BJ-5ta. (B) Quantification of AKT protein expression and p-AKT activation levels normalised against Coomassie staining in BJ-5ta. (C) Representative images of fluorescence labelling of HeLa cells after transfection with GFP-tagged PTEN. (D) Normalised fluorescence of the 550 most fluorescent HeLa cells in each preparation

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