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Fig. 6 | Biology Direct

Fig. 6

From: Loss of the centrosomal protein ALMS1 alters lipid metabolism and the regulation of extracellular matrix-related processes

Fig. 6

Analysis of differentially expressed genes overlapping between transcriptome and proteome. (A) Venn diagram with differentially expressed genes in the transcriptome and proteome and matching terms in both datasets. (B) Correlation plot between Log2 FCs in the transcriptome and the proteome of the matched terms. (C) Fisher’s exact test to evaluate the probability of obtaining 75 or more matched genes. (D) Significantly over-represented (ORA, FDR < 0.05) GO terms that are associated with the subset of matched data. (E) Significantly over-represented pathways (ORA, FDR < 0.01) in the list of overlapping genes (F). Network clustering of GO terms and pathways in the different bases of the overlapping gene data after applying the Markov clustering algorithm (MCL).

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