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Fig. 4 | Biology Direct

Fig. 4

From: Loss of the centrosomal protein ALMS1 alters lipid metabolism and the regulation of extracellular matrix-related processes

Fig. 4

Protein expression profiling and enrichment analysis of ALMS1 knockout cell line (hTERT-BJ-5ta). (A) Heatmap of the 158 differentially expressed protein coding genes with FDR < 0.05 in the hTERT-BJ-5ta cell line after 24 h with TGF-β pathway stimulation (B) The 20 most statistically significant GO terms detected after over-representation analysis (ORA) in the proteome. BP: biological process; CC: cellular Component; MF: molecular function (C) Signalling pathways significantly enriched (ORA, FDR < 0.01) for proteomic data in Bioplanet, KEGG, MSigDB and Wikipathway databases

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Biology Direct

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