Fig. 3
From: p63 orchestrates serine and one carbon metabolism enzymes expression in head and neck cancer
p63 silencing decreases the expression of phosposerine phosphatase enzyme (PSPH) in FaDu. a Relative mRNA levels of genes involved in de novo serine biosynthesis (PHGDH, PSAT1 and PSPH) and OCM (MTHFD2) after p63 silencing for 48 h; b relative mRNA levels of PHGDH, PSAT1 and PSPH and MTHFD2 after p63 silencing for 72 h; c Western blot analysis of PHGDH, PSAT1, PSPH and MTHFD2 after 72 h of p63 silencing. d Relative ratio of PHGDH, PSAT1, PSPH and MTHFD2 after p63 silencing for 72 h, normalized protein levels. One representative experiment of 3 is shown. The p-value was obtained using ordinary one-way analysis of variance (ANOVA). Values were considered significant when p value < 0.05 (n.s. = not significant)