Fig. 1
From: p63 orchestrates serine and one carbon metabolism enzymes expression in head and neck cancer
Serine and one carbon metabolism enzymes are overexpressed and deregulated in HNSCC patients. a OncoPrint profiling of TP53, TP63, TP73, serine de novo and one carbon metabolism (OCM) enzymes alterations in HNSCC, analyzed from the TCGA Firehose Legacy dataset on the cBioportal platform. b Patients’ overlap analysis of expression alterations in the OCM and serine de novo genes with TP63 in HNSCC dataset analyzed on cBioportal. c Expression analysis of TP63 and serine de novo and OCM enzymes using a publicly available dataset of HNSCC (GSE12452). The p-value has obtained using Student’s t test with Welch’s correction. Values were considered significant with p value < 0.05 (n.s. = not significant)