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Fig. 5 | Biology Direct

Fig. 5

From: Long noncoding RNA KCNMA1-AS1 promotes osteogenic differentiation of human bone marrow mesenchymal stem cells by activating the SMAD9 signaling pathway

Fig. 5

KCNMA1-AS1 activates the SMAD9 signaling pathway when hBMSCs undergo osteogenic differentiation. A-B- The SMAD9 protein levels and phosphorylated SMAD9 (p-SMAD9) protein levels in hBMSCs transfected with lentivirus detected by western blot after one week of osteogenic induction. GAPDH served as the reference. C-D- The expression of total SMAD9 (C) and p-SMAD9 (D) in xenograft tissues evaluated by immunohistochemistry. Scale bar, 50 μm. ****P < 0.0001, in comparison to NC/sh-NC.

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