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Fig. 5 | Biology Direct

Fig. 5

From: Overexpression of ZNF488 supports pancreatic cancer cell proliferation and tumorigenesis through inhibition of ferroptosis via regulating SCD1-mediated unsaturated fatty acid metabolism

Fig. 5

ZNF488 upregulation of SCD1 promotes xenografted tumorigenesis. Ctrl, ZNF488 overexpressing and ZNF488 + shSCD1 PANC-1 stable cells lines were subcutaneously implanted into the nude mice for tumorigenesis. A The macroscopical images of tumors collected from the nude mice 37 days after cells implantation. B, C Tumor volume and body weight of the mice were monitored during tumorigenesis. D Tumors were weighted after sacrificing the mice. *p < 0.05. **p < 0.01

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