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Fig. 2 | Biology Direct

Fig. 2

From: Overexpression of ZNF488 supports pancreatic cancer cell proliferation and tumorigenesis through inhibition of ferroptosis via regulating SCD1-mediated unsaturated fatty acid metabolism

Fig. 2

ZNF488 promotes cell proliferation, colony formation and EdU cooperation. A siCtrl, siZNF488#1 and siZNF488#2 MIAPaCa-2 and PANC-1 cells were subjected to immunoblotting analysis with indicated antibodies. B, C Cell proliferation and growth were detected by CCK-8 and colony formation assay in siCtrl, siZNF488#1 and siZNF488#2 MIAPaCa-2 and PANC-1 cells. D EdU staining was analyzed in siCtrl, siZNF488#1 and siZNF488#2 MIAPaCa-2 and PANC-1 cells. E Ctrl and ZNF488 overexpressed MIAPaCa-2 and PANC-1 cells were subjected to immunoblotting analysis with indicated antibodies. F, G Cell proliferation and growth were detected by CCK-8 and colony formation assay in Ctrl and ZNF488 overexpressed MIAPaCa-2 and PANC-1 cells. H EdU staining was analyzed in Ctrl and ZNF488 overexpressed MIAPaCa-2 and PANC-1 cells. *p < 0.05. **p < 0.01

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Biology Direct

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