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Fig. 6 | Biology Direct

Fig. 6

From: Intranasal human-recombinant NGF administration improves outcome in children with post-traumatic unresponsive wakefulness syndrome

Fig. 6

SPECT before and after the treatment with hr-NGF. a, b: Perfusion SPECT images before (a) and after (b) hr-NGF administration. 99mTc-HMPAO SPECT images (transaxial slices) before hr-NGF treatment showed a severe reduction in radiotracer uptake (hypoperfusion) in all cortical regions of the left hemisphere. A moderate-to-severe reduction in 99mTc-HMPAO uptake was observed in the left subcortical areas, right cortical regions as well as right subcortical areas, whereas a mild reduction was detected in the cerebellum (a). After hr-NGF treatment, an increase in radiotracer uptake was found in the right frontal cortex (+ 16%), right temporal cortex (+ 20%), right parietal cortex (+ 14%), right occipital cortex (+ 26%) right and left thalamus (7.5% and 9%, respectively) and cerebellum (+ 34%) (b)

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