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Fig. 2 | Biology Direct

Fig. 2

From: Intranasal human-recombinant NGF administration improves outcome in children with post-traumatic unresponsive wakefulness syndrome

Fig. 2

SPECT before and after the treatment with hr-NGF. a, b: Perfusion SPECT images before (a) and after b intranasal hr-NGF administration. 99mTc-HMPAO SPECT images (transaxial slices) before hr-NGF treatment showed a mild reduction in radiotracer uptake (hypoperfusion) in the right and left parietal cortices, left frontal cortex, right temporal cortex, left temporal pole, as well as in the caudate nucleus, putamen and thalamus, bilaterally (a). After hr-NGF treatment, a slight increase in 99mTc-HMPAO uptake was detected in the left frontal cortex (+ 10%), right temporal cortex (+ 9%), left temporal pole (+ 13%), right and left caudate nucleus (+ 10% and + 11%, respectively), right and left putamen (+ 17% and + 15%, respectively), right and left thalamus (+ 11% and + 10%, respectively) (b)

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