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Table 2 Statistically significant DE cfRNAs in CSF of “all” at T6 compared to T0

From: Preliminary insights into RNA in CSF of pediatric SMA patients after 6 months of nusinersen

 

mRNA

lncRNA

Other biotype

DE cfRNAs in “all” at T6 vs T0

Up-regulated

13

0

7

Down-regulated

23

1

4

Subtotal

36

1

11

Total

48

  1. mRNAs, lncRNAs and “other biotype” (processed pseudogenes, unprocessed pseudogene and untranscribed unprocessed pseudogenes) number is represented in terms of up-regulated transcripts, down-regulated transcripts, subtotal and total. Transcripts were considered as DE when |log2(T6/T0)| was ≥ 0.5 and a FDR was ≤ 0.1