Table 1 Baseline characteristics of mice
From: Discovery biomarker to optimize obeticholic acid treatment for non-alcoholic fatty liver disease
Obeticholic acid (n = 19) | Vehicle (n = 8) | p-value | |
|---|---|---|---|
Metabolic factors | |||
Weight | 41.5 ± 2.5 | 41.3 ± 4.0 | 0.92 |
Liver histological findings | |||
Total NAFLD activity score | 4.2 ± 1.7 | 3.0 ± 1.6 | 0.35 |
Steatosis score | 2.1 ± 0.8 | 1.5 ± 1.1 | 0.18 |
Lobular inflammation score | 1.1 ± 1.1 | 0.5 ± 0.7 | 0.19 |
Hepatocellular ballooning score | 1.0 ± 0.0 | 1.0 ± 0.0 | 1.00 |