Did the early full genome sequencing of yeast boost gene function discovery?

Biology Direct

Table 1 The number of S. cerevisiae genes as well as sums of literature scores in various FPE ranges

FPE score range	#Genes	Percentage of the total 6691 genes (%)	Literature score	Percentage of total score (%)	ƩGenes	Category
0	640	9.57	0.00	0.00	640	Not studied
0 < x < 1	1447	21.63	395.02	0.39	4120	Very understudied
1 ≤ x < 5	1714	25.62	4622.60	4.62
5 ≤ x < 10	959	14.33	6886.99	6.88
10 ≤ x < 15	530	7.92	6542.36	6.54	1062	Understudied
15 ≤ x < 20	307	4.59	5297.69	5.30
20 ≤ x < 25	225	3.36	5014.21	5.01
25 ≤ x < 30	152	2.27	4152.95	4.15	344	Moderately studied
30 ≤ x < 35	103	1.54	3355.06	3.35
35 ≤ x < 40	89	1.33	3318.26	3.32
40 ≤ x < 45	71	1.06	2999.29	3.00	290	Intensively studied
45 ≤ x < 50	61	0.91	2908.25	2.91
50 ≤ x < 75	158	2.36	9670.73	9.67
75 ≤ x < 100	66	0.99	5688.36	5.69	235	Very intensively studied
100 ≤ x < 500	155	2.32	26,730.43	26.72
x ≥ 500	14	0.21	12,465.79	12.46
Total	6691		100,048			–

This table lists the results of the automated mapping of publications onto the genome of baker’s yeast. We present the total number of genes in the respective FPE range at the time of this study (“#Genes”). We added a row for the 640 genes not specifically mentioned in any article about S. cerevisiae published until our cut-off date. Also, we computed the sum of the literature score for all genes in the respective FPE range (“Literature Score”). The total literature score 100,048 is equal to the total number of articles found with referencing a yeast gene in the main text, abstract or title. The FPE score range is further classified into six categories and the total number of genes in that category is provided (“ΣGenes”)

ISSN: 1745-6150