Fig. 4

Adoptively transferred ILC1s inhibit the tumor growth by promoting the M1-like phenotype macrophage polarization. A–C the tumor graph, tumor weight, and tumor volume in 2 × 10⁵ ILC1s adoptively transferred mice and control mice. D Representative flow cytometry graphs of getting the tumor tissue macrophage. E CD86 MFI of macrophage (CD45⁺F4/80⁺CD86⁺) in the tumor of ILC1s adoptively transferred mice and control mice was detected by flow cytometry. F CD206 MFI of macrophage (CD45⁺F4/80⁺CD206⁺) in the tumor of ILC1s adoptively transferred mice and control mice was detected by flow cytometry. G Western blotting was used to detect the expression of iNOS and Arg-1 in the tumor of ILC1s adoptively transferred mice and control mice. H Representative flow cytometry graphs of getting the tumor tissue ILC1s in different groups. I Percentage of ILC1s in different groups. J Representative flow cytometry getting strategy of the tumor tissue IFN-γ in different groups. K The expression level of IFN-γ in the tumor of ILC1s adoptively transferred mice and control mice. All the experiments repeated for 3 times, n = 5. Data are shown as mean ± SD (n = 5 per group, *p < 0.05, **p < 0.01, ***p < 0.001, and ****p < 0.0001)