Fig. 1
From: Pro-tumorigenic role of lnc-ZNF30-3 as a sponge counteracting miR-145-5p in prostate cancer
Expression patterns of miR-145-5p, TWIST1 and EMT markers is associated with different stages of prostate cancer progression and prognosis. A. Expression of miR-145-5p in the epithelial compartment of PCa tissues annotated as Gleason Low (n = 4), Gleason Intermediate (n = 4) and Gleason High (n = 8)-grade, relative to normal prostate (n = 5). Four patients with Gleason High-grade pathology developed metastases. * P-value < 0.05 (Kruskal-Wallis test; error bars indicate mean +/- sem). B. Quantification of miR-145-5p and TWIST1 mRNA levels in the TCGA PRAD data according to the Gleason score [28]. C. Survival analysis of the TCGA PRAD cohort based on expression data of miR-145-5p and TWIST1.