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Fig. 3 | Biology Direct

Fig. 3

From: ANKRD29, as a new prognostic and immunological biomarker of non–small cell lung cancer, inhibits cell growth and migration by regulating MAPK signaling pathway

Fig. 3

Promoter hypermethylation induced ANKRD29 low expression in NSCLC. A Methylation levels in normal tissues and LUAD or LUSC tissues from SMART website. B-C ANKRD29 expression was detected by qRT-PCR (B) and immunoblot (C) in NSCLC cells treated with 5-Azacytidine (5-Aza) or DMSO. The red arrow indicated the target band of ANKRD29 protein. D Four ANKRD29 CpG sites of high methylation levels including cg26522239, cg04164415, cg13421439 and cg26822986 predicted a poor prognosis. Bars are the mean value ± SD. ns = no significant. * P < 0.05, ** P < 0.01, *** P < 0.001

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Biology Direct

ISSN: 1745-6150

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