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Fig. 2 | Biology Direct

Fig. 2

From: ANKRD29, as a new prognostic and immunological biomarker of non–small cell lung cancer, inhibits cell growth and migration by regulating MAPK signaling pathway

Fig. 2

Five ANKRD genes were dysregulated in NSCLC. A-B Expression levels of the five ANKRD genes between NSCLC and normal tissues from TCGA cohorts. C-D Correlation analysis between five risk factors expression and stages of NSCLC were performed. E The Kaplan-Meier survival analysis of five ANKRDs expression in TCGA NSCLC dataset. F ROC curves of indicated genes in NSCLC from TCGA database. G Venn diagram analysis of 13 DEGs from five GEO datasets of NSCLC. The 13 DEGs were CLDN18, STXBP6, PTPRB, PDK4, BTNL9, ADRB1, EMCN, ABI3BP, GIMAP8, ROBO4, HHIP, ANKRD29 and ADAMTS8. H Relative mRNA and protein expression levels of ANKRD29 in NSCLC cell lines including A549, H1299, SPC-A1, H1975 and H1650. Normal human bronchial epithelial cells 16HBE as control. ROC: receiver operating characteristic; TCGA: The Cancer Genome Atlas. Bars are the mean value ± SD. ns = no significant. * P < 0.05, ** P < 0.01, *** P < 0.001

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Biology Direct

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