Fig. 8
From: Mir-421 and mir-550a-1 are potential prognostic markers in esophageal adenocarcinoma
Prediction of target mRNAs and establishment of a microRNA (miRNA)–mRNA axis and Gene ontology enrichment and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis of the 20 target mRNAs. A, B, and C overlapped target mRNAs were analyzed using the predicted target mRNAs, differentially expressed genes (DEGs) associated with esophageal adenocarcinoma, and significantly-downregulated mRNAs, respectively. D miRNA–mRNA network was constructed using the three miRNAs for EAC prognosis and 20 overlapped target mRNAs. E Biological process. F Molecular function. G KEGG pathways