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Fig. 5 | Biology Direct

Fig. 5

From: A genome-wide search of Toll/Interleukin-1 receptor (TIR) domain-containing adapter molecule (TICAM) and their evolutionary divergence from other TIR domain containing proteins

Fig. 5

The figure in the top panel shows a representative phylogeny for TRIF (A), TRAM (B) and TAG (C) respectively. The colored region represents organisms from different taxa and the node colour represents previously categorised ZEBRA subfamily. D This panel represents the evolutionary timeline from TICAM origin from Leptocardii and divergence into TRIF, TRAM and TAG. Here, TRAM was seen to be lost in Coelacanthimorpha and Actniopteri. The time period for the organisms were taken from Time Tree considering divergence between the hits. The order of the Eras with their Periods are Neo-Proterozoic Era (Cryogenian and Ediacaran), Paleozoic Era (Cambrian, Ordovician, Silurian, Devonian, Mississippian, Pennsylvanian, Carboniferous, and Permian), Mesozoic Era (Triassic, Jurassic and Cretaceous) and Cenozoic Era (Paleogene, Neogene and Quaternary)

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