Skip to main content
Fig. 6 | Biology Direct

Fig. 6

From: Circ_0067680 expedites the osteogenic differentiation of human bone marrow-derived mesenchymal stem cells through miR-4429/CTNNB1/Wnt/β-catenin pathway

Fig. 6

Circ_0067680 contributes to the progression of osteogenic differentiation of hBMSCs via targeting miR-4429/CTNNB1 axis. A CTNNB1 expression was elevated in hBMSCs and was verified by RT-qPCR. B CCK-8 assay exmained hBMSCs viability. C ALP accumulation was observed in hBMSCs transfected with sh-NC, sh-circ_0067680#1, sh_circ_0067680#1 + miR-4429 inhibitor and sh-circ_0067680#1 + pcDNA3.1/CTNNB1 plasmids. D, E Expression of RUNX2, OSX and OCN was tested in the sh-NC group, sh-circ_0067680#1 group, sh-circ_0067680#1 + miR-4429 inhibitor group and sh-circ_0067680#1 + pcDNA3.1/CTNNB1 group. **P < 0.01

Back to article page

Biology Direct

ISSN: 1745-6150

Contact us