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Fig. 2 | Biology Direct

Fig. 2

From: Molecular mechanisms of the juvenile form of Batten disease: important role of MAPK signaling pathways (ERK1/ERK2, JNK and p38) in pathogenesis of the malady

Fig. 2

CLN1, CLN2, CLN3, CLN5, CLN6, CLN7, CLN8 and CLN10 proteins can be connected in a single protein network. The protein network was generated by using software tool esyN (http://www.esyn.org/) integrated with major databases. Red ovals represent NCL proteins, blue ovals – protein residents of the endoplasmic reticulum, yellow ovals – plasma membrane proteins. Red lines with perpendicular bar at their ends and red arrows indicate negative (inhibitory) or positive (activatory) effects of the corresponding protein interactions

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