Fig. 4From: Biochemical and biophysical characterization of cell-free synthesized Rift Valley fever virus nucleoprotein capsids enables in vitro screening to identify novel antiviralsInhibitory small molecules identified using the CFPS have an inhibitory effect in live virus assay. a Various compounds demonstrated a dose-dependent inhibition of RVFV NP assembly in the plate assay. b Similar compounds were effective against LASV NP assembly. c The selected “hit” compounds were potent in the live virus assay for both RVFV and LASV. d Exposure of the compounds to HEK-293 cells indicates no toxicity in their active concentrationBack to article page