Class | BLASTP | CS-BLAST | DELTA-BLAST | PSI-BLAST | CSI-BLAST |
---|
A | 0.061 | (0.0003) | 0.084 | (0.0005) |
0.192
| (0.0009) | 0.172 | (0.0008) |
0.192
| (0.0012) |
B | 0.095 | (0.0003) | 0.108 | (0.0004) |
0.356
| (0.0013) | 0.285 | (0.0022) | 0.267 | (0.0028) |
C | 0.062 | (0.0002) | 0.096 | (0.0009) |
0.189
| (0.0015) | 0.163 | (0.0013) | 0.173 | (0.0015) |
D | 0.166 | (0.0004) | 0.198 | (0.0007) |
0.471
| (0.0009) | 0.443 | (0.0009) | 0.452 | (0.0008) |
E | 0.263 | (0.0013) | 0.276 | (0.0011) |
0.459
| (0.0046) | 0.415 | (0.0023) | 0.439 | (0.0029) |
F | 0.376 | (0.0026) | 0.391 | (0.0034) |
0.563
| (0.0029) | 0.474 | (0.0019) | 0.530 | (0.0072) |
G | 0.066 | (0.0010) | 0.059 | (0.0014) | 0.120 | (0.0010) |
0.133
| (0.0010) | 0.123 | (0.0021) |
- We divided the pooled search results into subsets, according to the SCOP protein class of the query and computed ROC
n
scores for each subset, with n equal to the number of queries in each class. See the legend of Figure 2 for data set description. The rows represent SCOP protein classes: A - All alpha proteins (866 queries), B - All beta proteins (1034 queries), C - Alpha and beta proteins a/b (1310 queries), D - Alpha and beta proteins a + b (1219 queries), E - Multi-domain proteins (78 queries), F - Membrane and cell surface proteins and peptides (64 queries), and G - Small proteins (284 queries). The columns show ROC
n
scores and standard errors for each method. The largest scores per row are in bold font.