Mass action models versus the Hill model: An analysis of tetrameric human thymidine kinase 1 positive cooperativity

Table 1 Models that contributed more than 5% to a model average.

Dataset	Model	Weight	K₁	K₂	K₃	K₄	k₁	k₂	k₃	k₄
1	DDDD.DDDM	0.444	1.28	1.28	1.28	1.28	4.99	4.99	4.99	4.11
1	DDDD.DDLL	0.298	0.72	0.72	0.72	0.72	2.91	2.91	4.18	4.18
1	DDDM.DDDD	0.219	1.02	1.02	1.02	0.56	4.12	4.12	4.12	4.12
2	DDDM.DDDD	0.978	0.76	0.76	0.76	0.20	7.02	7.02	7.02	7.02
3	DFFF.DDDD	0.393	1.32	0.54	0.54	0.54	3.92	3.92	3.92	3.92
3	DDDD.DFFF	0.335	0.53	0.53	0.53	0.53	0.96	3.93	3.93	3.93
3	DDDD.DDLL	0.204	0.36	0.36	0.36	0.36	1.35	1.35	3.80	3.80
3	DDLL.DDDD	0.059	0.90	0.90	0.41	0.41	3.80	3.80	3.80	3.80
4	DFFF.DDDD	0.400	0.65	0.49	0.49	0.49	4.67	4.67	4.67	4.67
4	DDDD.DFFF	0.314	0.48	0.48	0.48	0.48	3.50	4.67	4.67	4.67
4	DDLL.DDDD	0.118	0.57	0.57	0.48	0.48	4.66	4.66	4.66	4.66
4	DDDD.DDDM	0.074	0.60	0.60	0.60	0.60	5.01	5.01	5.01	4.67
5	DFFF.DDDD	0.545	1.62	0.53	0.53	0.53	0.27	0.27	0.27	0.27
5	DDLL.DDDD	0.234	1.08	1.08	0.32	0.32	0.26	0.26	0.26	0.26
5	DDDD.DFFF	0.192	0.56	0.56	0.56	0.56	0.06	0.28	0.28	0.28

ISSN: 1745-6150