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Figure 1 | Biology Direct

Figure 1

From: Functional insight into Maelstrom in the germline piRNA pathway: a unique domain homologous to the DnaQ-H 3'–5' exonuclease, its lineage-specific expansion/loss and evolutionarily active site switch

Figure 1

Multiple sequence alignment of representatives of MAEL domain. The sequences are represented by an abbreviation of species name followed by database entry ID. The homologues of C. savignyi identified in Ensembl database are indicated by Cs1 and Cs2. The consensus in 80% of the sequences is shown below the alignment based on default amino acid classes in Chroma. The numbers in bracket are indicative of the excluded residues from sequences. For a complete multiple sequence alignment refer to additional file 1. Species name abbreviations: Aa, Aedes aegypti; Ag, Anopheles gambiae; Am, Apis mellifera; Cb, Caenorhabditis briggsae; Ce, Caenorhabditis elegans; Ci, Ciona intestinalis; Cs,Ciona savignyi; Dm, Drosophila melanogaster; Ed, Entamoeba dispar SAW760; Eh, Entamoeba histolytica; Gg, Gallus gallus; Gm, Glossina morsitans; Hs, Homo sapiens; Md, Monodelphis domestica; Lb, Leishmania braziliensis; Tb, Trypanosoma brucei TREU927; Tr, Trypanosoma congolense; Tv, Trypanosoma vivax; Xt, Xenopus tropicalis.

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